Research and development at APL covers a full circle of scientific, engineering, and technical activities from around the Laboratory and beyond. The authors of the articles in this issue reside in seven APL departments, and there are several external co-authors. The articles describe some of APL’s work in applied research (information retrieval, optimization techniques and resource access), technology (laser-based ultrasonics), biomedical research (laser eye safety, pain sensation and wound characterization), and injury prevention biomechanics (crash-induced neck injuries and non-penetrating bullet wounds).